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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD2
All Species:
27.27
Human Site:
S416
Identified Species:
60
UniProt:
O14939
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14939
NP_002654.3
933
105987
S416
L
G
I
N
S
G
Y
S
K
R
A
L
M
L
L
Chimpanzee
Pan troglodytes
XP_511291
924
105027
S416
L
G
I
N
S
G
Y
S
K
R
A
L
M
L
L
Rhesus Macaque
Macaca mulatta
XP_001117754
892
101098
V407
H
H
E
K
L
L
V
V
D
Q
V
V
A
F
L
Dog
Lupus familis
XP_536610
854
96426
H393
G
R
D
F
I
Q
L
H
R
H
D
S
Y
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P97813
933
106150
S416
L
G
I
N
S
G
Y
S
K
R
T
L
M
L
L
Rat
Rattus norvegicus
P70498
933
106019
S416
L
G
I
N
S
G
Y
S
K
R
T
L
M
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422793
1072
123414
S432
L
G
I
N
S
E
Y
S
K
R
T
L
M
H
L
Frog
Xenopus laevis
NP_001129642
1039
119219
S435
L
G
I
N
S
E
Y
S
K
R
T
L
L
R
I
Zebra Danio
Brachydanio rerio
XP_694649
927
106849
S404
L
G
I
N
S
G
Y
S
K
R
K
L
M
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194932
825
94056
R364
G
E
D
V
P
D
G
R
A
K
Q
A
R
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
S447
L
K
I
N
S
L
Y
S
K
K
R
L
Q
N
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
92.1
77.2
N.A.
90
89.5
N.A.
N.A.
48.8
50.9
59.2
N.A.
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
97.2
93.7
80.7
N.A.
93.8
93.1
N.A.
N.A.
63.3
66.2
73.5
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
100
6.6
0
N.A.
93.3
93.3
N.A.
N.A.
80
66.6
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
6.6
N.A.
93.3
93.3
N.A.
N.A.
80
80
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
19
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
10
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
10
10
0
0
19
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
19
64
0
0
0
46
10
0
0
0
0
0
0
0
0
% G
% His:
10
10
0
0
0
0
0
10
0
10
0
0
0
10
0
% H
% Ile:
0
0
73
0
10
0
0
0
0
0
0
0
0
0
19
% I
% Lys:
0
10
0
10
0
0
0
0
73
19
10
0
0
0
0
% K
% Leu:
73
0
0
0
10
19
10
0
0
0
0
73
10
37
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% M
% Asn:
0
0
0
73
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
10
10
0
10
0
10
% Q
% Arg:
0
10
0
0
0
0
0
10
10
64
10
0
10
10
0
% R
% Ser:
0
0
0
0
73
0
0
73
0
0
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
10
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
73
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _